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Friday 11 December 2009

Hepatorenal Toxicity in 3 approved GM food crops


These substances have never before been an integral part of the human or animal diet and therefore their health consequences for those who consume them, especially over long time periods are currently unknown.

A new peer reviewed study by the independent Crigen Laboratories and published in the esteemed International Journal of Biological Sciences concludes that# GM crops, namely MON 863, MON 810 and NK 603 previously approved by the European Genetically Modified Regulatory Authority (EFSA) and by other countries should now be recalled and be animal feeding studiesd for at least two years.

For the first time comparative blood and organ analysis of rats fed three main commercialized genetically modified (GM) maize (NK 603, MON 810, MON 863), which are present in food and feed in the world. NK 603 has been modified to be tolerant to the broad spectrum herbicide Roundup. MON 810 and MON 863 are engineered to synthesize two different Bacillus thuringiensis-derived proteins (Bt) toxins used as insecticides. As a result, the potential effects on physiological parameters, due either to the recognized mutagenic effects of the GM transformation process or to the presence of the above mentioned novel pesticides within these plants can be evaluated in animal feeding studies.
The analysis highlights that the kidneys and liver as particularly important on which to focus such research as there was a clear negative impact on the function of these organs in rats consuming GM maize varieties for just 90 days.
Effects were mostly associated with the kidney and liver, the dietary detoxifying organs, although different between the 3 GMOs. Other effects were also noticed in the heart, adrenal glands, spleen and haematopoietic system.
They conclude that the data highlights signs of hepatorenal toxicity, possibly due to the new pesticides specific to each GM corn. These substances have never before been an integral part of the human or animal diet and therefore their health consequences for those who consume them, especially over long time periods are currently unknown. Furthermore, any side effect linked to the GM event will be unique in each case as the site of transgene insertion and the spectrum of genome wide mutations will differ between the three modified maize types.
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